Medicine for treating allergic disease

アレルギー疾患処置剤

Abstract

(57)【要約】 【課題】 III型アレルギー反応に起因する疾患の有効 な処置剤を提供する。 【解決手段】 下記一般式(I)で表されるレシチン化 スーパーオキシドジスムターゼを有効成分とする、III 型アレルギー反応に起因する疾患の処置剤。 SOD’(Q−B) m (I) (式中、SOD’はスーパーオキシドジスムターゼの残 基を表し、Qは化学的架橋を表し、Bはグリセロールの 2位に水酸基を有するリゾレシチンのその水酸基の水素 原子を除いた残基を表し、mはスーパーオキシドジスム ターゼ1分子に対するリゾレシチンの平均結合数であっ て、1以上の正数を表す。)
PROBLEM TO BE SOLVED: To provide a treating medicine which is effective for diseases caused by the type III allergic reaction. SOLUTION: This medicine for treating a disease caused by the type III allergic reaction, containing as an active ingredient a lecithinized superoxide dismutase represented by the general formula (I): SOD'(Q-B)m (I) [SOD' is the residue of the superoxide dismutase; Q is a chemical cross-link; B is a residue obtained by removing a hydrogen atom from the hydroxyl group of lysolecithin in which the hydroxyl group is placed at the 2-position of glycerol; (m) is a positive number of >=1 and is the average bond number of the lysolecithin per superoxide dismutase molecule].

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    WO-2008075706-A1June 26, 2008Ltt Bio-Pharma Co., Ltd.Therapeutic agent for interstitial pneumonia
    WO-2010064522-A1June 10, 2010株式会社Lttバイオファーマ修飾型スーパーオキサイドジスムターゼ含有吸入剤
    WO-2010103959-A1September 16, 2010株式会社LttバイオファーマAmeliorating agent for chronic obstructive pulmonary disease